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Triethylenethiophosphoramide

WebJan 1, 1992 · This article is cited by 24 publications. Mark Seierstad, Mark S. Tichenor, Renee L. DesJarlais, Jim Na, Genesis M. Bacani, De Michael Chung, Eduardo V. Mercado … Web噻替哌(英語: ThioTEPA或thiotepa ,又名塞替派、硫涕巴),化学全称N,N',N''-三亚乙基硫代磷酰胺,是一种用来治疗癌症的烷化剂。. 噻替哌是一种有机磷化合物,分子式为SP(NC 2 H 4) 3 。 它是N,N',N''-三亚乙基硫代磷酰胺(涕巴或TEPA)的衍生物。 噻替哌的分子结构与四面体磷结构及磷酸酯结构十分相似 ...

Intrathecal n, n′, n′‐triethylenethiophosphoramide [thio‐tepa (NSC …

WebToxicity, metabolism, and tissue distribution of carbon 14-labeled N,N′,N″-triethylenethiophosphoramide (Thio-TEPA) in rats ☆ WebThiotepa (Thioplex, Tiofosyl, Tiofosfamid, Triethylenethiophosphoramide) is an alkylating agent used to treat cancer. Protocol (from reference) Solubility (25°C) In vitro. Chemical … fittings plus https://cray-cottage.com

TriethylenethiophosphoraMide CAS:52-24-4 Amadis Chemical …

WebMar 2, 2004 · The alkylating agents cyclophosphamide (CP) and N, N ′, N ″-triethylenethiophosphoramide (thiotepa) are often co-administered in high-dose … WebINTRODUCTION The cytotoxic drug triethylenethiophosphoramide (ThioTEPA, Fig. l), is being used currently in a controlled randomised trial to examine the contri- … WebSection XI - TOXICOLOGICAL INFORMATION See RTECS (R) database for a complete list of toxicity data for Thiotepa: RTECS # SZ2975000 LD50 oral, mouse = 38 mg/kg LD50 subcutaneous, mouse = 16.5 mg/kg LD50 oral, rat = 23 mg/kg LD50 intravenous, mouse = 14.5 mg/kg LD50 intraperitoneal, rat = 8 mg/kg LD50 intramuscular, mouse = 11.5 mg/kg … fittings plastic

INTRATHECAL N, N

Category:THIOTEPA - World Health Organization

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Triethylenethiophosphoramide

Simultaneous quantification of cyclophosphamide, 4 ...

WebJan 9, 2024 · Malignant involvement of the pericardium is seen in 1 to 20 percent of autopsies in patients with cancer. The most common metastatic tumor involving the … WebDec 21, 2024 · Visit ChemicalBook To find more Triethylenethiophosphoramide(52-24-4) information like chemical properties,Structure,melting point,boiling point,density,molecular formula,molecular weight, physical properties,toxicity information,customs codes. You …

Triethylenethiophosphoramide

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WebJan 14, 2024 · 塞替派生物活性. Thio-TEPA 是一种 DNA 烷化剂 (DNA alkylator),具有抗肿瘤作用。. Thio-TEPA在大鼠肝切片孵育中表现出烷化活性。. Thio-TEPA不影响大鼠肝切片 … WebTechnical details about Triethylenethiophosphoramide, learn more about the structure, uses, toxicity, action, side effects and more

WebThiotepa (INN), sold under the brand name Tepadina, is a medication used to treat cancer.. Thiotepa is an organophosphorus compound with the formula (C 2 H 4 N) 3 PS. It is an analog of N,N′,N′′-triethylenephosphoramide (TEPA), which contains tetrahedral phosphorus and is structurally akin to phosphate.It is manufactured by heating aziridine with … WebOct 15, 2007 · Galal H. Elgemeie, Reham A. Mohamed-Ezzat, in New Strategies Targeting Cancer Metabolism, 2024 3 Aziridines. Aziridinium cation is the active species that is …

WebINTRATHECAL N, N', N"- TRIETHYLENETHIOPHOSPHORAMIDE [THIO-TEPA (NSC MENINGEAL DISEASE Phase I-11 Study 6396)] IN THE TREATMENT OF MALIGNANT … WebBelow 50 u/ml recoveries were 95 [plus or minus]5%. The absorption and fate of the labeled drug were studied in dogs and humans after intravenous and oral administration. After intravenous administration of Cl4-thio-TEPA to dogs in the presence of N,N [image],N"-triethylene-phosphoramide (TEPA) was demonstrated in the urine.

WebEinecs: 200-135-7. Description: Quick Details Common Name Thio-TEPA CAS Number 52-24-4 Molecular Weight. Updatetime: Nov 25 2024. Appearance: solid or liquid ( refer to COA) …

WebMar 2, 2004 · The alkylating agents cyclophosphamide (CP) and N, N ′, N ″-triethylenethiophosphoramide (thiotepa) are often co-administered in high-dose … can i get depressed while sickWebRequest PDF Quantification of N, N’ N’’-triethylenethiophosphoramide, N, N’ N’’-triethylenephosphoramide, cyclophosphamide, and 4-hydroxy-cyclophosphamide in … can i get deleted pictures backWebES262759A1 ES0262759A ES262759A ES262759A1 ES 262759 A1 ES262759 A1 ES 262759A1 ES 0262759 A ES0262759 A ES 0262759A ES 262759 A ES262759 A ES … can i get diameter from circumference numberWebUse of triethylenethiophosphoramide as an adjuvant to the surgical treatment of gastric and colorectal carcinoma: ten-year follow-up Ann Surg. 1971 Jan;173(1):26-39. doi: … can i get dental benefits with tricareWebOct 1, 1976 · N, N′, N″‐Triethylenethiophosphoramide [Thio‐TEPA (NSC 6396)] is the third drug to be evaluated for the treatment of meningeal neoplasia. Eleven patients with … can i get disability for adhd in a childWebThio-TEPA (N,N′N′-triethylenethiophosphoramide) is used as a cancer chemotherapeutic, alkylating agent. It is used to treat various kinds of cancer such as breast, ovarian and … can i get direct tv stream on my fire tabletWeb本发明涉及了可从以下过程中获得的生物碱反应产物:生物碱与烃化剂(最好是硫替派)进行反应,之后通过水洗或利用适当的水溶剂洗涤,将未反应的烃化剂和其它溶于水的成分从反应混合物中去除,然后利用强酸,最好是硫化氢(HCl)对反应混合物进行处理,以沉淀反应物的水溶性盐。沉淀的 ... can i get different booster shot