WebAug 19, 2024 · STAT1 is a master regulator that orchestrates type 1 and 2 interferon (IFN)-induced IFN-stimulated gene (ISG) expression. The mechanisms by which STAT1 is phosphorylated and activated upon IFN ... WebNational Center for Biotechnology Information
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WebDec 1, 2024 · For ChIP or ChIP-seq, antibodies included Normal Rabbit IgG (CST #2729), STAT1 pS727 (Life Tech #44-382G) or STAT1α/β (Santa Cruz sc-346). For STAT1 ChIP-seq, for each treatment group, three sets of 3.3 × 10 7 cells were independently pulled down with 15 μg of antibody, then pooled into 2 replicates at the library prep stage. WebMay 4, 2024 · 3 Key Laboratory of Laparoscopic Technology, The First Affiliated Hospital of Shandong First Medical University, Jinan, China. 4 Department of Peripheral Vascular Disease, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China. PMID: 34017248. PMCID: PMC8129022. DOI: 10.3389/fphar.2024.614044.
WebIFNγ is a cytokine with important roles in tissue homeostasis, immune and inflammatory responses and tumour immunosurveillance. Signalling by the IFNγ receptor activates the Janus kinase (JAK)-signal transducer and activator of transcription 1 (STAT1) pathway to induce the expression of classical interferon-stimulated genes that have key immune … WebJan 27, 2024 · STAT1 is a transcription factor that is known to modulate cell apoptosis signaling. In myocardial I/R injury, STAT1 was activated in apoptotic cardiomyocytes and enhanced apoptosis by upregulating ...
WebNov 17, 2014 · Antibodies targeted to p-p65, STAT1, SOCS-1, JAK1, p-JAK1 and phosphotyrosine-specific STAT1 (Tyr 701) Ab were obtained from Cell Signaling Technology (Boston, Massachusetts, USA). Anti-MyD88 … WebDec 17, 2024 · After incubation with anti-p-Stat1 (Tyr701) antibody (CST, Danvers, MA) or normal rabbit IgG overnight at 4 °C with rotation, and then 30 μl of ChIP-grade Protein G magnetic beads was added and ...
WebCell Signaling Technology's Phospho-Stat1 (Tyr701) (58D6) Rabbit mAb is a Rabbit monoclonal antibody. The Phospho-Stat1 (Tyr701) (58D6) Rabbit mAb Antibody was generated using STAT1 as the antigen. It reacts with Human, and Mouse. This antibody has been shown to work in applications such as: Precipitation, Sequencing, ChIP-Seq, ChIP, …
WebAug 19, 2024 · Introduction. Type 1 interferon (IFN) signaling is crucial for the host defense against pathogenic infection and autoimmune diseases; thus, the production and downstream events of type 1 IFN are tightly regulated [].Type 1 IFN is produced in three major pathways: the TLR3- and TLR4-mediated TIR domain-containing adapter-inducing … floris bvba kontichWebThe Stat1 Antibody confirms silencing of Stat1 expression, and the p42 MAPK Antibody is used to control for protein loading and siRNA … great wolf lodge refund covidWebSTAT1 and pSTAT1 Ser727 expression in patient samples, as previously described.7 Tissue sections were incubated with pri-mary antibody including, STAT1 (D1K9Y) rabbit … floriscent lights bad for concussionsWebApr 14, 2024 · Since LINC02574 depletion impaired IFN production and STAT1 activation, this prompted us to further investigate the effect of LINC02574 on the expression of RIG-I, TLR3, and MDA5, the three important PRRs that recognize the invading influenza virus and mediate the production of IFNs. ... (Tyr701), anti-phospho-STAT3 (Tyr705) (Cell … floris cafe torinoWebMonoclonal Antibody for studying Stat1. Cited in 325 publications. Validated for WB, IP, IHC, IF, F, ChIP, C&R. Available in 2 sizes. Highly specific … great wolf lodge queue itWebDec 1, 2010 · We first demonstrate that STAT1 can interact directly with the G1 cell cycle regulatory cyclin D1 and CDK4 proteins, suggesting a role for STAT1 in G1 cell cycle … floris coldplayWebDec 31, 2024 · The Stat1 Antibody from Cell Signaling Technology is a Rabbit Polyclonal antibody to STAT1. This antibody recognizes Human, … great wolf lodge rate calculator